Back 4 Blood is set in a post-apocalyptic world that has been taken over by Ridden (basically zombies). While the plot is not exactly deep, the characters and atmosphere do a lot of the storytelling for you. Plays can pick from 8 survivors that all have unique background stories and abilities to contribute to a 4-man team. These characters, known as cleaners, provide not only unique weapons but a few class traits such as Holly who offers a boost in team stamina, recovers stamina with kills, and has damage resistance. She also carries a spiked bat to take off the heads of Ridden, and a shotgun to crack a hole in their chest. Another great example is Jim, who on the other hand gets bonus precision kill damage, ADS speed, and team weakspot damage. He sports a nasty sniper rifle providing excellent backup for team compositions. Each character has their own reasons for finding enjoyment in tearing apart the ridden, and provides great commentary as your team fires away at endless enemies to try and survive.
The scenery of the game is a strong suit for this horror survival and not just the interesting types of Ridden. The environment is graphically breathtaking, but also shows the hardship that the people have gone through with what has become the end of the world. Buildings and blood-covered and torn apart, bridges are covered in rubble, and corpses lie amuck with a strong possibility of waking to kill you. Many of the NPCs have great dialogue and show the fear from their voices as they hide or help. The only place that gives any sense of security is the base camp where players can upgrade their cards and practice.